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Human Mesenchymal Stromal Cells Improve Cardiac Perfusion in an Ovine Immunocompetent Animal Model

Victor Dayan, Veronica Sotelo, Valentina Delfina, Natalia Delgado,Carlos Rodriguez, Carol Suanes, María Langhain, Rodolfo Ferrando, Armand Keating, Alejandro Benech, Cristina Touriño

J Invest Surg 2016 Aug 18;29(4):218-25. Epub 2016 Feb 18.

Mesenchymal stromal cells (MSCs) hold considerable promise in the treatment of ischemic heart disease. Most preclinical studies of MSCs for acute myocardial infarction (AMI) have been performed either in syngeneic animal models or with human cells in xenogeneic immunodeficient animals. A preferable pre-clinical model, however, would involve human MSCs in an immunocompetent animal. …

–Source: https://www.researchgate.net/publication/295078443_Human_Mesenchymal_Stromal_Cells_Improve_Cardiac_Perfusion_in_an_Ovine_Immunocompetent_Animal_Model

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