Interdisciplinary research team tackles remaining hurdles to using stem cells to reverse heart failure

A story on one of the 19 University of Toronto Medicine By Design (MbD) projects using regenerative medicine to advance healthcare.  It is one of three projects currently being run by MbD that are using FailSafe.  This MbD project entitled  IMPROVING THE FUNCTION, INTEGRATION AND SAFETY OF STEM CELL-DERIVED CARDIOMYOCYTE TRANSPLANTATION (Laflamme, Keller, Cheng, Nagy) is using stem cell-derived cardiac muscle cells, or cardiomyocytes, to repair damaged muscle after a heart attack  .  The other two projects utilizing FailSafe are:  INTRODUCING FAIL-SAFE PLURIPOTENT CELLS INTO CLINICALLY RELEVANT CELL THERAPY APPLICATIONS (Nagy, Waddell, Post); and, .CELL TRANSPLANTATION FOR STROKE REPAIR (Moorshead, Nagy, Shoicet, Lipsman)

To learn more about this “Heart Team Project”, please click on the link:

When a person has a heart attack, working cardiac muscle dies and is replaced by scar tissue. Treatments are few and those that are available are mostly aimed at slowing the progression of the patient’s underlying heart disease, rather than restoring function to the damaged part of the heart.

But what if doctors could inject heart muscle cells derived from stem cells into the ailing organ to repair it? …